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Among the complex molecular processes involved in the development of bacteria-borne disease is quorum sensing, the way bacteria communicate and coordinate collective behaviors. By studying how to inhibit quorum sensing, scientists may be able create antibacterial pharmaceuticals for a variety of ailments.
Recently, in part due to work performed at NSLS, researchers from Princeton University and the Howard Hughes Medical Institute learned how to block a quorum-sensing mechanism in the bacteria Chromobacterium violaceum, commonly found in tropical soils and water. Although this pathogen rarely infects humans, the group’s success indicates that their work could lead to therapeutics for diseases caused by other bacteria types
Primary source: Molecular Cell